| Surgical decision making in temporal lobe epilepsy: A comparison of [(18)F]FDG-PET, MRI, and EEG. | |
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MedLine Citation:
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PMID: 21798813 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVES: The goals of this work were (1) to determine the effect of [(18)F]fluorodeoxyglucose positron emission tomography (FDG-PET), MRI, and EEG on the decision to perform temporal lobe epilepsy (TLE) surgery, and (2) to determine if FDG-PET, MRI, or EEG predicts surgical outcome. METHODS: All PET scans ordered (2000-2010) for epilepsy or seizures were tabulated. Medical records were investigated to determine eligibility and collect data. Statistical analysis included odds ratios, κ statistics, univariate analysis, and logistic regression. RESULTS: Of the 186 patients who underwent FDG-PET, 124 had TLE, 50 were surgical candidates, and 34 had surgery with post-operative follow-up. Median length of follow-up was 24months. MRI, FDG-PET, and EEG were significant predictors of surgical candidacy (P<0.001) with odds ratios of 42.8, 20.4, and 6.3, respectively. FDG-PET was the only significant predictor of postoperative outcome (P<0.01). CONCLUSION: MRI showed a trend toward having the most influence on surgical candidacy, but only FDG-PET predicted surgical outcome. |
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Authors:
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Aaron F Struck; Lance T Hall; John M Floberg; Scott B Perlman; Douglas A Dulli |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-7-26 |
Journal Detail:
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Title: Epilepsy & behavior : E&B Volume: - ISSN: 1525-5069 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-7-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100892858 Medline TA: Epilepsy Behav Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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Nuclear Medicine Section, Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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