Document Detail

Surgical Myectomy for Hypertrophic Obstructive Cardiomyopathy: The Cut That Heals.
MedLine Citation:
PMID:  23770749     Owner:  NLM     Status:  Publisher    
Hypertrophic cardiomyopathy (HCM) has been one of the most interesting and controversial disorders in cardiovascular medicine. Although initial descriptions of the pathology of hypertrophic cardiomyopathy (HCM) were published over a century ago, it was not until the surgical and pathological observations of Brock and Teare respectively that this cardiac entity came to attention in the modern era. HCM is a primary disorder of the myocardium characterized by myocyte hypertrophy and fibre disarray, myocardial fibrosis, and abnormal coronary intramural microvasculature. Although HCM is characterized by tremendous diversity in terms of phenotypic expression, genetic substrate, and clinical presentation, left ventricular outflow tract (LVOT) obstruction is an integral component of the disease, occurring in up to 70% of patients either at rest or with provocation(1).
Lynne Williams; Harry Rakowski
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-6-14
Journal Detail:
Title:  Circulation     Volume:  -     ISSN:  1524-4539     ISO Abbreviation:  Circulation     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-6-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
1Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
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