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Surgical or interventional revascularization in diabetic patients with coronary artery disease?
MedLine Citation:
PMID:  20879974     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
The combination of diabetes mellitus and coronary artery disease (CAD) constitutes an aggressive disease characterized biologically by chronic inflammatory, proliferative and pro-thrombotic situation. In the "diabetic patient" the increased frequency and gravity of simultaneous myocardial infarction and the deterioration of congestive heart failure contribute to the inevitable unfavourable final result. Diabetes accelerates the natural course of atherosclerosis and involves a great number of coronary vessels with more diffuse atherosclerotic lesions. Moreover, the risks of plaque ulceration and thrombosis have been shown to be considerably higher in diabetic patients. The treatment should be also aggressive and be based on the combined treatment of CAD and the effective regulation of glucose levels. The decision of revascularization in the diabetic patient should be posed relatively earlier. The surgical choice of revascularization seems to be advantageous over the interventional, with better early and late results.
Authors:
E Apostolakis; I Koniari; D Velissaris; Efstratios N Koletsis
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current diabetes reviews     Volume:  6     ISSN:  1875-6417     ISO Abbreviation:  Curr Diabetes Rev     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101253260     Medline TA:  Curr Diabetes Rev     Country:  United Arab Emirates    
Other Details:
Languages:  eng     Pagination:  359-66     Citation Subset:  IM    
Affiliation:
Department of Cardiothoracic Surgery, Department of Anaesthesiology and ICU, University of Patras, Patras, Greece.
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