Document Detail

Surgery for refractory glaucoma.
MedLine Citation:
PMID:  8985544     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To determine the surgical outcome of mitomycin trabeculectomy in patients with refractory glaucoma. METHODS: Sixty-six eyes of 52 patients with refractory glaucoma underwent mitomycin trabeculectomy. Mitomycin was applied for five minutes only once during trabeculectomy. The follow-up period was six to 61 months. RESULTS: Cumulative success probability was calculated using Kaplan-Meier life-table analysis assuming the cut-off postoperative IOP to be 20 mmHg or IOP reduction by at least 20% in eyes with preoperative IOP 24 mmHg. At the end of 61-month follow-up the success probability was 80% +/- 6% without postoperative ocular hypotensive medication (complete success) and was 95% +/- 3% regardless of postoperative antiglaucoma medication (overall success), respectively. CONCLUSION: The data suggest that mitomycin trabeculectomy is efficacious in reducing IOP in patients with refractory glaucoma.
Y Kitazawa; T Yamamoto; A Sawada; Y Hagiwara
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Australian and New Zealand journal of ophthalmology     Volume:  24     ISSN:  0814-9763     ISO Abbreviation:  Aust N Z J Ophthalmol     Publication Date:  1996 Nov 
Date Detail:
Created Date:  1997-03-04     Completed Date:  1997-03-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8505423     Medline TA:  Aust N Z J Ophthalmol     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  327-32     Citation Subset:  IM    
Department of Ophthalmology, Gifu University School of Medicine, Japan.
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MeSH Terms
Chemotherapy, Adjuvant
Follow-Up Studies
Glaucoma / drug therapy,  surgery*
Intraocular Pressure
Life Tables
Middle Aged
Mitomycin / administration & dosage*
Nucleic Acid Synthesis Inhibitors / administration & dosage*
Postoperative Complications
Risk Factors
Treatment Outcome
Reg. No./Substance:
0/Nucleic Acid Synthesis Inhibitors; 50-07-7/Mitomycin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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