Document Detail


Surgery and long-term follow-up of hepatic echinococcosis outside endemic regions
MedLine Citation:
PMID:  11857098     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of the study was to characterize the therapeutic pathways in patients with echinococcal hydatids in an institution outside the endemic areas but with a high frequency of oncological hepatic surgery.PATIENTS AND METHODS: 44 patients with echinococcosis from 1987-1997 were reviewed. To evaluate the long-term results, clinical examination, chest x-ray, serology and liver ultrasound were performed. According to the study protocol 39 patients were evaluable. 89.7 % of the patients suffered from a primary disease, whereas 7.7 had a local recurrence and another 2.5 of patients showed a second site of manifestation after former operation. E. cysticus occurred in 82.5 %, E. alveolaris in 17.5 %. RESULTS: In 66.7 % of all cases a resecting procedure (pericystectomy, atypic resection, regular and extended hemihepatectomy) was performed. One patient underwent an orthotopic liver transplantation and in 10 % the surgical procedure included only an open drainage of the cysts. A simple cystectomy was performed in 23 %. One patient died from multiple organ failure as a consequence of local bleeding complications. The overall complication rate was 38.5 %, including the postoperative death and 7.7 % reoperations. The complication rate following pericystectomy was much higher than after simple cystectomy. At the time of follow-up (median 66 months) no patient showed a recurrent disease. CONCLUSION: Compared to reports from endemic regions the rate of resective procedures was much higher. The therapeutic strategy lead to excellent long-term results. Simple cystectomy should be preferred as pericystectomy showed a higher morbidity.
Authors:
A Schmidt-Matthiesen; O Schott; A Encke
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Zeitschrift f?r Gastroenterologie     Volume:  40     ISSN:  0044-2771     ISO Abbreviation:  Z Gastroenterol     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-02-21     Completed Date:  2002-04-26     Revised Date:  2010-03-23    
Medline Journal Info:
Nlm Unique ID:  0033370     Medline TA:  Z Gastroenterol     Country:  Germany    
Other Details:
Languages:  ger     Pagination:  51-7     Citation Subset:  IM    
Affiliation:
Klinik f?r Allgemein- und Gef?sschirurgie, Klinikum der Johann-Wolfgang-Goethe-Universit?t, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany. Schmidt-Matthiesen@em.uni-frankfurt.de
Vernacular Title:
Die chirurgische Behandlung der Leberechinokokkose ausserhalb von Endemiegebieten und ihre Sp?tergebnisse.
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MeSH Terms
Descriptor/Qualifier:
Adult
Echinococcosis, Hepatic / diagnosis,  epidemiology,  surgery*
Endemic Diseases
Female
Follow-Up Studies
Germany
Humans
Length of Stay
Male
Mebendazole / administration & dosage
Middle Aged
Postoperative Care
Postoperative Complications / mortality,  surgery
Recurrence
Reoperation
Retrospective Studies
Survival Rate
Chemical
Reg. No./Substance:
31431-39-7/Mebendazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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