Document Detail

Surgery for focal epilepsy in the older patient.
MedLine Citation:
PMID:  1909773     Owner:  NLM     Status:  MEDLINE    
Eight of the 237 patients who received a surgical procedure for intractable partial epilepsy at the Mayo Clinic during a 3-year period were 50 years of age or older. All patients had disabling partial seizures of several years in duration that were refractory to antiepileptic drug medication. A neuroimaging-identified epileptogenic lesion prompted referral for surgical treatment in three patients. The only clinically significant morbidity associated with surgery in the eight patients was a transient exacerbation of an aphasia in a patient who underwent a left frontal corticectomy. All eight patients had a favorable seizure outcome, and three patients postoperatively are seizure free. Epilepsy surgery may be an appropriate alternate therapy for select patients in the sixth decade of life or older with medically refractory partial seizures.
G D Cascino; F W Sharbrough; K A Hirschorn; W R Marsh
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neurology     Volume:  41     ISSN:  0028-3878     ISO Abbreviation:  Neurology     Publication Date:  1991 Sep 
Date Detail:
Created Date:  1991-10-11     Completed Date:  1991-10-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1415-7     Citation Subset:  AIM; IM    
Department of Neurology, Mayo Clinic, Rochester, MN 55905.
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MeSH Terms
Anticonvulsants / adverse effects,  therapeutic use
Epilepsies, Partial / complications,  drug therapy,  surgery*
Middle Aged
Temporal Lobe / surgery
Reg. No./Substance:

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