| Surfactant treatment in a pediatric burn patient with respiratory failure. | |
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MedLine Citation:
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PMID: 10608328 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This report describes surfactant treatment in a burned infant with severe respiratory failure. In this patient the instillation of surfactant rapidly improved compliance, oxygen index (OI), and alveolar-capillary oxygen gradient (AaDO2), while the need for oxygen supplementation and peak positive pressure drastically decreased. The treatment was repeated after 12 hours. Although the baby had severe clinical course complications as a Gram-negative sepsis and a subglottic stenosis, she was weaned from oxygen therapy and mechanical ventilation in few weeks. Surfactant dysfunctions seem to play a central role in the respiratory insufficiency of burned patients, and its exogenous replacements could improve their outcome. |
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Authors:
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L Tortorolo; A Chiaretti; M Piastra; L Viola; G Polidori |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pediatric emergency care Volume: 15 ISSN: 0749-5161 ISO Abbreviation: Pediatr Emerg Care Publication Date: 1999 Dec |
Date Detail:
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Created Date: 2000-01-19 Completed Date: 2000-01-19 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8507560 Medline TA: Pediatr Emerg Care Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 410-1 Citation Subset: IM |
Affiliation:
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Pediatric Intensive Care Unit, Institute of Pediatrics, Catholic University of Rome, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Burns, Inhalation
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complications*,
therapy Child, Preschool Female Humans Pulmonary Surfactants / therapeutic use* Respiration, Artificial Respiratory Distress Syndrome, Adult / drug therapy*, etiology, physiopathology Respiratory Insufficiency / drug therapy*, etiology, physiopathology |
| Chemical | |
Reg. No./Substance:
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0/Pulmonary Surfactants |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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