Document Detail


Surfactant replacement therapy in acute respiratory distress syndrome from viral pneumonia.
MedLine Citation:
PMID:  8814477     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A modified natural surfactant was administered to a patient with life-threatening adult respiratory distress syndrome caused by viral pneumonia. Subsequently, there was a marked improvement in gas exchange. In order to assess the mechanism for improved oxygenation, computed tomography of the lungs was done. Quantitative analysis of the scans taken before and after surfactant administration indicates that improvement in gas exchange was largely due to the expansion of underinflated and collapsed lung areas. Although this is a single case report, it provides insight into the possible beneficial effect of instilled surfactant in severe respiratory distress from viral pneumonia.
Authors:
G Putz; C Hörmann; W Koller; G Schön
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Intensive care medicine     Volume:  22     ISSN:  0342-4642     ISO Abbreviation:  Intensive Care Med     Publication Date:  1996 Jun 
Date Detail:
Created Date:  1996-12-10     Completed Date:  1996-12-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7704851     Medline TA:  Intensive Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  588-90     Citation Subset:  IM    
Affiliation:
Division of Surgical and General Intensive Care Medicine, Clinic for Anesthesia, General Intensive Care Medicine, Innsbruck, Austria.
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MeSH Terms
Descriptor/Qualifier:
Biological Products*
Child, Preschool
Humans
Male
Phospholipids*
Pneumonia, Viral / complications
Pulmonary Gas Exchange / drug effects
Pulmonary Surfactants / therapeutic use*
Respiratory Distress Syndrome, Adult / etiology,  therapy*
Tomography, X-Ray Computed
Chemical
Reg. No./Substance:
0/Biological Products; 0/Phospholipids; 0/Pulmonary Surfactants; 129069-19-8/poractant alfa

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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