| Surfactant Therapy for Acute Lung Injury and Acute Respiratory Distress Syndrome. | |
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MedLine Citation:
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PMID: 21742216 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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This article examines exogenous lung surfactant replacement therapy and its usefulness in mitigating clinical acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS). Surfactant therapy is beneficial in term infants with pneumonia and meconium aspiration lung injury, and in children up to age 21 years with direct pulmonary forms of ALI/ARDS. However, extension of exogenous surfactant therapy to adults with respiratory failure and clinical ALI/ARDS remains a challenge. This article reviews clinical studies of surfactant therapy in pediatric and adult patients with ALI/ARDS, focusing on its potential advantages in patients with direct pulmonary forms of these syndromes. |
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Authors:
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Krishnan Raghavendran; D Willson; R H Notter |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Critical care clinics Volume: 27 ISSN: 1557-8232 ISO Abbreviation: Crit Care Clin Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-07-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8507720 Medline TA: Crit Care Clin Country: United States |
Other Details:
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Languages: eng Pagination: 525-59 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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Division of Acute Care Surgery, Department of Surgery, University of Michigan Health System, 1500 East Medical Center Drive, 1C340A-UH, SPC 5033, Ann Arbor, MI 48109-5033, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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