| Surface plasmon resonance shows a gender difference in circulating annexin A5 in human. | |
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MedLine Citation:
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PMID: 22483902 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The level of circulating anxA5 is correlated to various diseases such as acute myocardial infarction, trauma, thrombosis, inflammation and in some cancers. Our aim was to assess whether a direct approach using surface plasmon resonance (SPR) could be easily used to provide a rapid and cheap alternative to detect anxA5 in blood samples in human. Our results indicate that SPR permits to detect and quantify circulating anxA5 in serum with a minimum time of manipulation. Furthermore, we report here, for the first time, that the level of circulating anxA5 is significantly higher in male than in female (5.43 (±0.02) and 4.41 (±0.2)ng/ml, respectively). In conclusion, we found that SPR can be used to rapidly quantify anxA5 in patients and that a gender difference has to be taken into account to explain gender differences in the prevalence of some diseases. |
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Authors:
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Pascal Trouvé; Mathieu Kerbiriou; Sophie le Hir; Nathalie Benz; Claude Férec |
Publication Detail:
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Type: Journal Article Date: 2012-02-13 |
Journal Detail:
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Title: Talanta Volume: 93 ISSN: 1873-3573 ISO Abbreviation: Talanta Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-04-09 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2984816R Medline TA: Talanta Country: Netherlands |
Other Details:
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Languages: eng Pagination: 219-23 Citation Subset: IM |
Copyright Information:
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Copyright © 2012 Elsevier B.V. All rights reserved. |
Affiliation:
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Inserm, UMR1078, Brest F-29218, France; Université de Brest, Faculté de Médecine et des sciences de la santé, Brest F-29200, France. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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