| Surface modification of poly(oligoethylene oxide methacrylate) for resisting protein adsorption. | |
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MedLine Citation:
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PMID: 17141487 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We prepare poly(2-methoxyethyl-, 2-(2-methoxyethoxy)ethyl-, 2-[2-(2-methoxyethoxy)ethoxy]ethyl methacrylate) (p(nEOMA), n=1, 2, and 3) brushed surfaces with varying the polymer density by surface initiated polymerization. The amount of bovine serum albumin (BSA) adsorbed on the surfaces is investigated. The mobility of the polymer chain in the polymer/water interfaces and the structure of adsorbed water on the surfaces are characterized by Electron Spin Resonance (ESR) and transmission-Fourier transform infrared (FT-IR) spectroscopy, respectively. This work reports the relationship between these surface properties and albumin adsorption. As a result, the surface having both a high molecular mobility and bulk-like water found to be very effective in preventing albumin adsorption. |
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Authors:
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Tatsuya Tsukagoshi; Yukishige Kondo; Norio Yoshino |
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Publication Detail:
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Type: Journal Article Date: 2006-10-10 |
Journal Detail:
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Title: Colloids and surfaces. B, Biointerfaces Volume: 54 ISSN: 0927-7765 ISO Abbreviation: Colloids Surf B Biointerfaces Publication Date: 2007 Jan |
Date Detail:
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Created Date: 2007-01-02 Completed Date: 2007-03-07 Revised Date: 2009-10-16 |
Medline Journal Info:
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Nlm Unique ID: 9315133 Medline TA: Colloids Surf B Biointerfaces Country: Netherlands |
Other Details:
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Languages: eng Pagination: 94-100 Citation Subset: IM |
Affiliation:
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Department of Industrial Chemistry, Faculty of Engineering, Tokyo University of Science, 12-1 Ichigaya-Funagawara, Shinjuku-ku, Tokyo 162-0826, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adsorption Animals Cattle Electron Spin Resonance Spectroscopy Methacrylates / chemistry* Molecular Structure Polyethylene Glycols / chemistry* Serum Albumin, Bovine / chemistry* Silicon Dioxide / chemistry Spectroscopy, Fourier Transform Infrared Surface Properties Water / chemistry |
| Chemical | |
Reg. No./Substance:
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0/Methacrylates; 0/Polyethylene Glycols; 0/Serum Albumin, Bovine; 0/poly(oligoethylene oxide methacrylate); 7631-86-9/Silicon Dioxide; 7732-18-5/Water |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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