Document Detail


Surface blood flow and histology of human anterior cruciate ligament allografts.
MedLine Citation:
PMID:  2069629     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We measured surface blood flow in 53 anterior cruciate ligaments (ACLs) reconstructed with allogeneic tendon grafts using laser Doppler flowmetry and examined their histology through biopsy specimens procured during second-look arthroscopy to investigate the fate of ACL allografts on a long-term basis. The age of the grafts, i.e., time from the reconstruction to the second-look arthroscopy, ranged from 6 to 89 months. Six-month grafts showed significantly higher blood flow than the other older ones from 12 to 89 months, which showed a blood flow level equivalent to normal control ACLs. Histological studies revealed that ACL allografts remodeled with time, and that they reached stability by 18 months postimplantation. These results confirmed the concepts of age-dependent remodeling of allografts and their longevity in the human knee joint.
Authors:
K Shino; M Inoue; S Horibe; K Nakata; A Maeda; K Ono
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association     Volume:  7     ISSN:  0749-8063     ISO Abbreviation:  Arthroscopy     Publication Date:  1991  
Date Detail:
Created Date:  1991-08-16     Completed Date:  1991-08-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8506498     Medline TA:  Arthroscopy     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  171-6     Citation Subset:  IM    
Affiliation:
Department of Orthopaedic Surgery, Osaka University Medical School, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anterior Cruciate Ligament / blood supply,  transplantation*
Arthroscopy
Female
Graft Survival / physiology*
Humans
Male
Regional Blood Flow / physiology
Time Factors
Transplantation, Homologous

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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