Document Detail


Surface-assisted laser desorption and ionization mass spectrometry using low-cost matrix-free substrates.
MedLine Citation:
PMID:  21915949     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Surface-assisted laser desorption/ionization (SALDI) substrates have been fabricated using nanospiked polyurethane (PU) substrates that are replicated by a low-cost soft nanolithography method from silicon nanospike structures formed with femtosecond laser irradiations. The strongest mass spectrometry (MS) signal of Angiotensin II was obtained on 45-nm Au-coated nanospiked PU substrates. The effective ionization appears to be due to surface plasmon excitation. Such low-cost and identical SALDI substrates can be used for MS analysis of various molecules with high reproducibility. Copyright © 2011 John Wiley & Sons, Ltd.
Authors:
Haibin Huo; Mengyan Shen; Steven M Ebstein; Howard Guthermann
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of mass spectrometry : JMS     Volume:  46     ISSN:  1096-9888     ISO Abbreviation:  J Mass Spectrom     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-09-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9504818     Medline TA:  J Mass Spectrom     Country:  England    
Other Details:
Languages:  eng     Pagination:  859-64     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 John Wiley & Sons, Ltd.
Affiliation:
Department of Physics and Applied Physics, and Nanomanufacturing Center, University of Massachusetts Lowell, 1 University Avenue, Lowell, MA 01854, USA.
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