Document Detail


Surface area: a better predictor of disease severity than the height and volume of the barium column in patients with primary achalasia.
MedLine Citation:
PMID:  17033442     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Subjective assessment of primary achalasia is not accurate. We aimed to study the utility of surface area of barium retention in the objective assessment of these patients. METHODS: Subjective and objective esophageal functions of 99 patients with primary achalasia were evaluated initially and 43 of them were reevaluated 1 month after balloon dilation. RESULTS: Before dilation: Ninety-nine patients were enrolled. Forty-one of them were male. The mean age was 37.5+/-15.3 years. The mean score, resting lower esophageal sphincter pressure, height, surface and volume of barium retention at 5 min were 8.03+/-3.1, 59.1+/-20 mmHg, 9.9+/-4.9 cm, and 23.6+/-13.9 cm and 53.2+/-47.7 cm, respectively. Surface area at 5 min had best correlation and predictive value for resting lower esophageal sphincter pressure. After dilation: Forty-three of 99 patients were reevaluated after balloon dilation. The mean age was 36.8+/-13.6 years. Seventeen of them were male. Mean score, resting lower esophageal sphincter pressure, height, surface area and volume of barium retention at 5 min dropped significantly after dilation. Surface area at 5 min had best correlation and predictive value for lower esophageal sphincter pressure. CONCLUSIONS: Surface area of barium retention at 5 min is an accurate objective tool to assess patients with primary achalasia. It is cheap and easy to perform; therefore, it could be used more frequently in postdilation follow-up.
Authors:
Ghodrat Montazeri; Negin Nouri; Arezoo Estakhri; Shapoor Shirani; Shifteh Abedian; Atoosa Fazlollahi; Javad Mikaeli; Mehdi Nouraie; Reza Malekzadeh
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of gastroenterology & hepatology     Volume:  18     ISSN:  0954-691X     ISO Abbreviation:  Eur J Gastroenterol Hepatol     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-10-11     Completed Date:  2007-01-04     Revised Date:  2009-10-16    
Medline Journal Info:
Nlm Unique ID:  9000874     Medline TA:  Eur J Gastroenterol Hepatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  1203-8     Citation Subset:  IM    
Affiliation:
Digestive Disease Research Center, Tehran University of Medical Sciences, Shariati Hospital, Tehran, Iran. montazer@ams.ac.ir
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MeSH Terms
Descriptor/Qualifier:
Adult
Balloon Dilatation / methods
Barium Sulfate
Contrast Media
Esophageal Achalasia / pathology,  physiopathology,  radiography*
Esophagus / pathology,  physiopathology,  radiography*
Female
Follow-Up Studies
Humans
Logistic Models
Male
Manometry
Middle Aged
Peristalsis
Chemical
Reg. No./Substance:
0/Contrast Media; 7727-43-7/Barium Sulfate
Comments/Corrections
Comment In:
Nat Clin Pract Gastroenterol Hepatol. 2007 Jun;4(6):308-9   [PMID:  17457308 ]

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