Document Detail


Supravital fluorometric apoptosis detection in a single mouse embryo using lab-on-a-chip.
MedLine Citation:
PMID:  21833426     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Detection of apoptosis is one of the main criteria of preimplantation embryo growth potential assessment. Recent developments in lab-on-a-chip techniques has led to apoptosis detection and monitoring on a single cell or embryo level. However, single embryo apoptosis detection without a change in embryo developmental competence and post-examination "recovery" still remains a challenge. In this paper we present a lab-on-a-chip, co-working with miniaturized optical instrumentation, which allows supravital examination of single embryos for the presence of apoptotic blastomers with full after lab-on-a-chip study "recovery" and maintenance of their further developmental capacity.
Authors:
Rafał Walczak; Patrycja Sniadek; Jan A Dziuban; Joanna Kluger; Anna Chełmońska Soyta
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-11
Journal Detail:
Title:  Lab on a chip     Volume:  -     ISSN:  1473-0189     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101128948     Medline TA:  Lab Chip     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Wrocław University of Technology, Faculty of Microsystem Electronics and Photonics, Janiszewski Str. 11/17, 50-372, Wrocław, Poland. rafal.walczak@pwr.wroc.pl.
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