| Supraventricular tachycardia in Lown-Ganong-Levine syndrome: atrionodal versus intranodal reentry. | |
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MedLine Citation:
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PMID: 910716 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The mechanism of the abbreviated atrioventricular (A-V) nodal conduction time and paroxysmal supraventricular tachycardia in the Lown-Ganong-Levine syndrome was evaluated in six patients. In each the A-H interval increased in response to rapid atrial pacing and atrial extrastimuli; typical dual A-V nodal pathways were demonstrated. In five patients studied at two cycle lengths prolongation of conduction and refractoriness of the "fast" pathway was noted at the shorter basic cycle length. Propranolol prolonged conduction and refractoriness of the "fast" pathway in three patients and in one produced Wenckebach conduction during atrial pacing which did not occur prior to its administration. In three patients the atrium did not appear necessary to sustain supraventricular tachycardia. These findings suggest that preferential rapidly conducting A-V nodal fibers and intranodal reentry are the responsible mechanisms in those patients with Lown-Ganong-Levine syndrome and reciprocating tachycardia. |
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Authors:
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M E Josephson; J A Kastor |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The American journal of cardiology Volume: 40 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 1977 Oct |
Date Detail:
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Created Date: 1977-11-30 Completed Date: 1977-11-30 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 521-7 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Atrioventricular Node / drug effects, physiopathology* Cardiac Pacing, Artificial Electrocardiography Female Heart Conduction System / physiopathology* Humans Male Middle Aged Propranolol / diagnostic use Syndrome Tachycardia, Paroxysmal / etiology, physiopathology* |
| Chemical | |
Reg. No./Substance:
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525-66-6/Propranolol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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