| Supramolecular phospholipids-polyphenolics interactions: the PHYTOSOME strategy to improve the bioavailability of phytochemicals. | |
| | |
MedLine Citation:
|
PMID: 19919847 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The poor and/or erratic oral bioavailability of polyphenolics can be improved using the PHYTOSOME delivery system, a strategy that enhances the rate and the extent of solubilization into aqueous intestinal fluids and the capacity to cross biomembranes. Phospholipids show affinity for polyphenolics, and form supramolecular adducts having a definite stoichiometry. This article reviews the preparation and characterization of PHYTOSOME complexes and their activity in various medicinal (cardiovascular, anti-inflammatory, hepatoprotective, anticancer) and cosmetic (skin aging) realms of application. |
| | |
Authors:
|
Ajay Semalty; Mona Semalty; Mohan Singh Maniyari Rawat; Federico Franceschi |
Related Documents
:
|
8776317 - Factors influencing the response to advertisements for general practice vacancies. 3755567 - Forensic medicine and medicolegal investigation in sri lanka. 10359717 - Mass spectrometric analysis in combinatorial chemistry. 1865777 - Bayesian reasoning in medicine: the contributions of lee b. lusted, md. 9421257 - Isolation of mimengoside b, a triterpenoid saponin from buddleja madagascariensis. 2664357 - Ethnopharmacologic analysis of medicinal plants used by laotian hmong refugees in minne... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Review Date: 2009-11-14 |
Journal Detail:
|
Title: Fitoterapia Volume: 81 ISSN: 1873-6971 ISO Abbreviation: Fitoterapia Publication Date: 2010 Jul |
Date Detail:
|
Created Date: 2010-05-31 Completed Date: 2010-12-27 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 16930290R Medline TA: Fitoterapia Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 306-14 Citation Subset: IM |
Copyright Information:
|
Copyright 2009 Elsevier B.V. All rights reserved. |
Affiliation:
|
Department of Pharmaceutical Sciences, HNB Garhwal University Srinagar, Garhwal, India. semaltyajay@gmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Biological Availability Biological Transport Cardiovascular Diseases / drug therapy Cosmetics Flavonoids / chemistry, pharmacokinetics*, therapeutic use Humans Inflammation / drug therapy Intestines Liposomes / chemical synthesis* Liver Diseases / drug therapy Neoplasms / drug therapy Phenols / chemistry, pharmacokinetics*, therapeutic use Phospholipids* / chemistry Phytotherapy / methods* Plant Extracts / pharmacokinetics*, therapeutic use Solubility |
| Chemical | |
Reg. No./Substance:
|
0/Cosmetics; 0/Flavonoids; 0/Liposomes; 0/Phenols; 0/Phospholipids; 0/Plant Extracts; 0/polyphenols |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: HPMA copolymers: origins, early developments, present, and future.
Next Document: Quaternary structure of KATP channel SUR2A nucleotide binding domains resolved by synchrotron radiat...