Document Detail


Supramolecular metal displacement allows on-fluorescence analysis of manganese(II) in living cells.
MedLine Citation:
PMID:  23023093     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Due to the importance of Mn(2+) ions in biological processes, it is of growing interest to develop protocols for analysis of Mn(2+) uptake and distribution in cells. A supramolecular metal displacement assay can provide ratiometric fluorescence detection of Mn(2+), allowing for quantitative and longitudinal analysis of Mn(2+) uptake in living cells.
Authors:
Francesca Gruppi; Jian Liang; Benjamin B Bartelle; Maksim Royzen; Daniel H Turnbull; James W Canary
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  48     ISSN:  1364-548X     ISO Abbreviation:  Chem. Commun. (Camb.)     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-10-08     Completed Date:  2013-03-18     Revised Date:  2013-11-14    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  England    
Other Details:
Languages:  eng     Pagination:  10778-80     Citation Subset:  IM    
Affiliation:
Department of Chemistry, New York University, New York, NY 10003, USA.
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MeSH Terms
Descriptor/Qualifier:
Cadmium / chemistry*
Cell Line
Cell Survival
Fluorescence*
Fluorescent Dyes / chemistry*
HEK293 Cells
Humans
Macromolecular Substances / chemistry
Magnesium / analysis*,  pharmacokinetics
Grant Support
ID/Acronym/Agency:
GM076202/GM/NIGMS NIH HHS; NS038461/NS/NINDS NIH HHS; R01 NS038461/NS/NINDS NIH HHS
Chemical
Reg. No./Substance:
0/Fluorescent Dyes; 0/Macromolecular Substances; 7439-95-4/Magnesium; 7440-43-9/Cadmium
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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