Document Detail


Supra-normal creatinine clearance in black mild hypertensive patients in Nigeria.
MedLine Citation:
PMID:  3244147     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Glomerular filtration rates, as assessed by creatinine clearances were studied in 35 mild hypertensive, 104 moderate hypertensive and 167 severe hypertensive patients. The ages ranged from 16 to 65 years and the duration of hypertension varied between 0.5 and five years. The cause of hypertension was presumed idiopathic in all but 13 severe hypertensives in whom renal biopsies were performed. The mean creatinine clearances in mild, moderate and severe hypertensives were 154.5 +/- 15.0, 83.0 +/- 26.0, 15.0 +/- 14.0 (male) and 147.0 +/- 20.0, 78.0 +/- 15.0 and 14.3 +/- 13.0 (female) respectively. A creatinine clearance of greater than 125 ml per minute was recorded in all patients with mild hypertension. This finding might be a feature of early structural and functional renal damage in mild hypertension.
Authors:
T A Odutola; S B Ositelu; E A D'Almeida; J C Okeiyi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of human hypertension     Volume:  2     ISSN:  0950-9240     ISO Abbreviation:  J Hum Hypertens     Publication Date:  1988 Aug 
Date Detail:
Created Date:  1989-06-02     Completed Date:  1989-06-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8811625     Medline TA:  J Hum Hypertens     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  133-4     Citation Subset:  IM    
Affiliation:
Dialysis Centre, Lagos University Teaching Hospital, Nigeria.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Creatinine / analysis,  metabolism*
Female
Glomerular Filtration Rate
Humans
Hypertension / metabolism*
Male
Middle Aged
Chemical
Reg. No./Substance:
60-27-5/Creatinine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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