| Is the Suppressor-mutator element controlled by a basic developmental regulatory mechanism? | |
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MedLine Citation:
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PMID: 2848747 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report the results of genetic studies on derivatives of two different alleles of the maize a locus with an insertion of the Suppressor-mutator (Spm) transposable element in which the element is inactive, but can be reactivated readily. We present evidence that the mechanism that determines whether the element is in an active or inactive phase has two genetically distinguishable components. One determines whether or not the element is genetically active (the phase setting) and the other determines the stability of the setting in development, its heritability, and its phase in the next generation (the phase program). We show that the element's phase can be reset in a reproducible pattern during plant development. We also show that the Spm element can be reprogrammed to undergo a subsequent phase change without a concomitant phase change. The capacity to reset and reprogram the Spm element is differentially expressed within the plant in a pattern that is correlated with the developmental fate of apical and lateral meristems, suggesting the involvement of a basic developmental determination mechanism. |
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Authors:
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N V Fedoroff; J A Banks |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Genetics Volume: 120 ISSN: 0016-6731 ISO Abbreviation: Genetics Publication Date: 1988 Oct |
Date Detail:
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Created Date: 1989-01-13 Completed Date: 1989-01-13 Revised Date: 2010-09-09 |
Medline Journal Info:
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Nlm Unique ID: 0374636 Medline TA: Genetics Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 559-77 Citation Subset: IM |
Affiliation:
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Department of Embryology, Carnegie Institution of Washington, Baltimore, Maryland 21210. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Alleles Chromosome Mapping DNA Transposable Elements* Female Gene Expression Regulation* Male Mutation* Phenotype Suppression, Genetic* Zea mays / genetics*, growth & development |
| Grant Support | |
ID/Acronym/Agency:
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5-R01-GM34296-02/GM/NIGMS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/DNA Transposable Elements |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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