Document Detail


Suppressive effect of sera from patients undergoing chronic hemodialysis on neutrophil chemiluminescence response.
MedLine Citation:
PMID:  8210566     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To determine the mechanism of easy infectability of uremic patients, we studied the effect of sera from uremic patients who were undergoing chronic hemodialysis on the chemiluminescence (CL) response of polymorphonuclear leukocytes (PMN). The luminol-dependent CL response was examined following stimulation with phorbol myristate acetate (PMA) and N-formyl-methionyl-leucyl-phenylalanine (FMLP). The patient's sera suppressed the CL response following stimulation by PMA, but not by FMLP. These findings suggest that sera from uremic patients undergoing hemodialysis contain a suppressive substance that suppresses the activation of PMNs by PMA.
Authors:
T Matsumoto; S Kubo; K Takahashi; M Haraoka; M Tanaka; J Kumazawa; K Yoshimine; T Fukumitsu; Y Mihara; K Takayama
Related Documents :
11501646 - A questionnaire for the assessment of pruritus: validation in uremic patients.
9391686 - Baclofen toxicity in patients with severely impaired renal function.
572836 - Eosinophilia in maintenance hemodialysis patients.
8321366 - Isoniazid-induced neurotoxicity in chronic dialysis patients: report of three cases and...
300566 - Pulmonary infiltrates and fever in patients with hematologic malignancy: assessment of ...
11059096 - Low dose treatment with methotrexate-adverse drug reactions survey.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Renal failure     Volume:  15     ISSN:  0886-022X     ISO Abbreviation:  Ren Fail     Publication Date:  1993  
Date Detail:
Created Date:  1993-11-18     Completed Date:  1993-11-18     Revised Date:  2008-05-21    
Medline Journal Info:
Nlm Unique ID:  8701128     Medline TA:  Ren Fail     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  529-32     Citation Subset:  IM    
Affiliation:
Department of Urology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Chemiluminescent Measurements
Female
Humans
Lymphocyte Activation
Male
Middle Aged
N-Formylmethionine Leucyl-Phenylalanine / pharmacology
Neutrophils / drug effects,  physiology*
Renal Dialysis*
Respiratory Burst / physiology
Tetradecanoylphorbol Acetate / pharmacology
Uremia / blood*,  therapy
Chemical
Reg. No./Substance:
16561-29-8/Tetradecanoylphorbol Acetate; 59880-97-6/N-Formylmethionine Leucyl-Phenylalanine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Impaired antioxidant defense mechanisms in two children with hemolytic-uremic syndrome.
Next Document:  Diagnosis and treatment of carpal tunnel syndrome.