| Suppression of recurrent transient ischemic attacks by a statin agent. | |
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MedLine Citation:
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PMID: 11222801 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Recent studies of hydroxy-methylglutaryl coenzyme A reductase inhibitors have demonstrated that therapy with statins is associated with a significant decrease in the risk of stroke and TIA in patients with coronary artery disease. The underlying mechanism responsible for this effect is unclear. The author presents two patients who had cessation of TIAs upon institution of statin therapy. A variety of non-lipid-lowering mechanisms may account for this beneficial effect. This initial observation, if confirmed by further study, may suggest a role for statin agents in preventing recurrent TIAs. |
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Authors:
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M J Alberts |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Neurology Volume: 56 ISSN: 0028-3878 ISO Abbreviation: Neurology Publication Date: 2001 Feb |
Date Detail:
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Created Date: 2001-03-06 Completed Date: 2001-04-05 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0401060 Medline TA: Neurology Country: United States |
Other Details:
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Languages: eng Pagination: 531-2 Citation Subset: AIM; IM |
Affiliation:
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Stroke Acute Care Unit, Duke University Medical Center, Durham, NC, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Anticholesteremic Agents / therapeutic use* Female Humans Ischemic Attack, Transient / drug therapy*, physiopathology* Male Middle Aged Pravastatin / therapeutic use* Recurrence Stroke / prevention & control |
| Chemical | |
Reg. No./Substance:
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0/Anticholesteremic Agents; 81093-37-0/Pravastatin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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