| Suppression of melatonin secretion in healthy subjects with eyeglass LED delivery system. | |
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MedLine Citation:
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PMID: 20588229 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Practicability remains a problem in light therapy of biological rhythm disorders. We report here the effect on melatonin secretion of a device consisting of a prototype of eyeglasses including light emitting diodes (LED) in lenses (Somnavue). METHODS: Light (1,200 lx) was administered in a randomised crossover design to ten healthy subjects with Somnavue for 1 or 2 hours, Lumino (a helmet which administers light) for 1 hour, and placebo, beginning at 01:00 h. Plasma melatonin concentrations were evaluated between 20:00-05:00 h. RESULTS: Multiple comparisons showed differences between placebo and Somnavue administered for one or two hours (p<0.01 and p<0.05 respectively) and Lumino and placebo (p<0.05). CONCLUSIONS: In conclusion, Somnavue was able to suppress melatonin. The development of such a device could increase adherence with light treatment in SAD or circadian rhythm sleep disorders. |
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Authors:
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Bruno Claustrat; Jocelyne Brun; Françoise Borson-Chazot; Denis Cohen-Tannoudji; Francine Claustrat; Jacqueline Julien; Patrick Lemoine |
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Publication Detail:
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Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Neuro endocrinology letters Volume: 31 ISSN: 0172-780X ISO Abbreviation: Neuro Endocrinol. Lett. Publication Date: 2010 |
Date Detail:
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Created Date: 2010-07-23 Completed Date: 2010-10-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8008373 Medline TA: Neuro Endocrinol Lett Country: Sweden |
Other Details:
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Languages: eng Pagination: 330-5 Citation Subset: IM |
Affiliation:
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INSERM, U846, Bron, France. bruno.claustrat@chu-lyon.fr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Circadian Rhythm / physiology Energy Transfer Humans Melatonin / blood, secretion* Photic Stimulation / instrumentation* Phototherapy / instrumentation |
| Chemical | |
Reg. No./Substance:
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73-31-4/Melatonin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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