Document Detail


Suppression of lymphocyte response to concanavalin A by mucopolysaccharide material from Treponema pallidum-infected rabbits.
MedLine Citation:
PMID:  159264     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The testicular fluid and serum from rabbits infected intratesticularly with Treponema pallidum inhibited the mitogenic response of normal rabbit peripheral blood lymphocytes to concanavalin A. Mucopolysaccharide material present in the testicular fluid and serum was associated with the lymphocyte-inhibitory activity. Degradation of the mucopolysaccharide material with hyaluronidase resulted in the loss of the inhibitory activity of testicular fluid and serum of T. pallidu-infected rabbits.
Authors:
R F Bey; R C Johnson; T J Fitzgerald
Related Documents :
15097944 - Nonpseudomonal ecthyma gangrenosum.
21268974 - Application of the survey protocol for chytridiomycosis to queensland, australia.
9276604 - Hypercalcemia in a patient with hypoparathyroidism and nocardia asteroides infection: a...
2735654 - Sustained hypertransfusion and induction of a transplantable myeloid leukemia in rlv-a-...
24004524 - Development and validation of taqman probe based real time pcr assays for the specific ...
23699424 - Capnocytophaga related pulmonary infection in an immunocompetent host.
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Infection and immunity     Volume:  26     ISSN:  0019-9567     ISO Abbreviation:  Infect. Immun.     Publication Date:  1979 Oct 
Date Detail:
Created Date:  1980-01-28     Completed Date:  1980-01-28     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0246127     Medline TA:  Infect Immun     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  64-9     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Concanavalin A
Glycosaminoglycans / blood,  physiology*
Hyaluronoglucosaminidase / pharmacology
Lymphocyte Activation*
Male
Rabbits
Syphilis / blood,  immunology*
Chemical
Reg. No./Substance:
0/Glycosaminoglycans; 11028-71-0/Concanavalin A; EC 3.2.1.35/Hyaluronoglucosaminidase
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Depression of contact sensitivity by Pseudomonas aeruginosa-induced suppressor cells which affect th...
Next Document:  Augmentation of lymphocyte surface immunogenicity following treatment with dimethyl-sulphoxide.