Document Detail

Suppression of defective-sporulation phenotypes by mutations in the major sigma factor gene (rpoD) of Bacillus subtilis.
MedLine Citation:
PMID:  3932823     Owner:  NLM     Status:  MEDLINE    
Mutations (crsA47 and crsA4) in the major sigma factor gene (rpoD) of Bacillus subtilis RNA polymerase have been found to be powerful intergenic suppressors of spoOB, spoOE, spoOF, spoOK and spoIIG mutations. The crsA47 suppressor restores sporulation of spoOE, spoOF, spoOK and spoIIG mutants to levels near those of wild type bacteria and substantially improves the sporulation of a spoOB strain. The crsA mutations are shown to prevent the induction by aliphatic alcohols of SpoO phenocopies in wild type B. subtilis cells.
A Leung; S Rubinstein; C Yang; J W Li; T Leighton
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Molecular & general genetics : MGG     Volume:  201     ISSN:  0026-8925     ISO Abbreviation:  Mol. Gen. Genet.     Publication Date:  1985  
Date Detail:
Created Date:  1985-12-18     Completed Date:  1985-12-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0125036     Medline TA:  Mol Gen Genet     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  96-8     Citation Subset:  IM    
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MeSH Terms
Bacillus subtilis / genetics*
Genes, Bacterial*
Sigma Factor / genetics*
Species Specificity
Spores, Bacterial / physiology
Suppression, Genetic*
Transcription Factors / genetics*
Reg. No./Substance:
0/Sigma Factor; 0/Transcription Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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