| Suppression of deep brain stimulation artifacts from the electroencephalogram by frequency-domain Hampel filtering. | |
| | |
MedLine Citation:
|
PMID: 20362499 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: Currently, electroencephalography (EEG) cannot be used to record cortical activity during clinically effective DBS due to the presence of large stimulation artifact with components that overlap the useful spectrum of the EEG. A filtering method is presented that removes these artifacts whilst preserving the spectral and temporal fidelity of the underlying EEG. METHODS: The filter is based on the Hampel identifier that treats artifacts as outliers in the frequency domain and replaces them with interpolated values. Performance of the filter was tested with a synthesized DBS signal and actual data recorded during bilateral monopolar DBS. RESULTS: Mean increases in signal-to-noise ratio of 7.8dB for single-frequency stimulation and 13.8dB for dual-frequency stimulation are reported. Correlation analysis between EEG with synthesized artifacts and artifact-free EEG reveals that distortion to the underlying EEG in the filtered signal is negligible (r(2)>0.99). CONCLUSIONS: Frequency-domain Hampel filtering has been shown to remove monopolar DBS artifacts under a number of common stimulation conditions used for the treatment of Parkinson's disease. SIGNIFICANCE: Application of frequency-domain Hampel filtering will allow the measurement of EEG in patients during clinically effective DBS and thus may increase our understanding of the mechanisms of action of this important therapeutic intervention. |
| | |
Authors:
|
David P Allen; Elizabeth L Stegemöller; Cindy Zadikoff; Joshua M Rosenow; Colum D Mackinnon |
Related Documents
:
|
11137669 - Information flow from the sensorimotor cortex to muscle in humans. 11295759 - The 980-nm diode laser as a new stimulant for laser evoked potentials studies. 15587809 - Spectral correlation studies of emotional states in humans. 12202099 - Motion and ballistocardiogram artifact removal for interleaved recording of eeg and eps... 17202479 - High thalamocortical theta coherence in patients with parkinson's disease. 20682469 - On the stability of the n:m phase synchronization index. 3411049 - Rate coding model for discrimination of simple tones in the presence of noise. 14680769 - The perceived direction and speed of global motion in glass pattern sequences. 16811499 - Measuring flicker thresholds in the budgerigar. |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural Date: 2010-04-01 |
Journal Detail:
|
Title: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology Volume: 121 ISSN: 1872-8952 ISO Abbreviation: Clin Neurophysiol Publication Date: 2010 Aug |
Date Detail:
|
Created Date: 2010-07-15 Completed Date: 2010-07-30 Revised Date: 2011-08-03 |
Medline Journal Info:
|
Nlm Unique ID: 100883319 Medline TA: Clin Neurophysiol Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 1227-32 Citation Subset: IM |
Copyright Information:
|
Copyright 2010 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
|
Department of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL IL 60611,, USA. dp_allen@ieee.org |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Artifacts* Brain / physiopathology* Brain Mapping / methods Deep Brain Stimulation / methods* Electrodes, Implanted Electroencephalography / methods* Humans Image Processing, Computer-Assisted Parkinson Disease / physiopathology*, therapy Signal Processing, Computer-Assisted Software |
| Grant Support | |
ID/Acronym/Agency:
|
R01-NS054199/NS/NINDS NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Corticomotoneuronal function in asymptomatic SOD-1 mutation carriers.
Next Document: Cortical sources of EEG rhythms are abnormal in down syndrome.