| Suppression by kampo medicine, sho-saiko-to, on papillomas induced by 7,12-dimethylbenz(a)anthracene in mice. | |
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MedLine Citation:
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PMID: 7872238 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Sho-saiko-to (SST) is a Japanese modified, traditional Chinese herbal medicine (Kampo medicine) consisting of seven medical plants. We examined the effects of SST on formation and growth of squamous cell papillomas induced by 7,12-dimethylbenz(a)anthracene application in mouse skin. Chronic oral administration of SST reduced the incidence and growth of papillomas with the reduction of activities of succinate-dehydrogenase and thymidylate synthetase, which were evaluated as the cell viability and DNA synthesis via the de novo pathway, respectively. |
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Authors:
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L Liu; S Sakamoto; T Nakayama; H Kudo; S Suzuki; M Matsubara; H Nagasawa |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American journal of Chinese medicine Volume: 22 ISSN: 0192-415X ISO Abbreviation: Am. J. Chin. Med. Publication Date: 1994 |
Date Detail:
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Created Date: 1995-03-29 Completed Date: 1995-03-29 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7901431 Medline TA: Am J Chin Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 267-74 Citation Subset: IM |
Affiliation:
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Medical Research Institute, Tokyo Medical and Dental University, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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9,10-Dimethyl-1,2-benzanthracene* Animals Drugs, Chinese Herbal / therapeutic use* Male Mice Mice, Inbred ICR Papilloma / chemically induced, drug therapy* Skin Neoplasms / chemically induced, drug therapy* Succinate Dehydrogenase / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Drugs, Chinese Herbal; 57-97-6/9,10-Dimethyl-1,2-benzanthracene; EC 1.3.99.1/Succinate Dehydrogenase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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