Document Detail


Suppressed aggression and hyperdynamic cardiovascular regulation in normotensive offspring of essential hypertensive parents.
MedLine Citation:
PMID:  2467098     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To trace a possible association between suppressed aggression and enhanced responses of the cardiovascular system and plasma catecholamines in a "prehypertensive" state, two groups of 24 subjects with either normal blood pressure and no family history of hypertension or normal blood pressure and a positive family history of hypertension were matched for sex and age (18-24 years). Suppressed aggression was defined by the Rosenzweig Picture-Frustration test, a projective assessment of reactions to everyday stress. Before, during, as well as after application of mental stressors (Stroop color-word conflict test and mental arithmetic), the responses of blood pressure, heart rate, and venous plasma catecholamines were measured. Offspring of hypertensive parents with suppressed aggression (n = 10) had significantly higher heart rates and diastolic blood pressures than offspring of hypertensive parents without suppressed aggression (n = 14), using analyses of covariance for repeated measures to eliminate the influence of anxiety. Plasma norepinephrine responses tended to be greater in the offspring with suppressed aggression. The results suggest that in normotensive offspring of hypertensive parents, a behavioral pattern with suppressed aggression promotes a hyperdynamic cardiovascular state and enhances the hypertensive developmental process.
Authors:
C Perini; F B Müller; F R Bühler
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of cardiovascular pharmacology     Volume:  12 Suppl 3     ISSN:  0160-2446     ISO Abbreviation:  J. Cardiovasc. Pharmacol.     Publication Date:  1988  
Date Detail:
Created Date:  1989-05-05     Completed Date:  1989-05-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7902492     Medline TA:  J Cardiovasc Pharmacol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  S130-3     Citation Subset:  IM    
Affiliation:
Department of Medicine, University Hospital, Basel, Switzerland.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aggression / physiology*
Blood Pressure
Conflict (Psychology)
Electrocardiography
Female
Heart Rate
Hemodynamics*
Humans
Hypertension / genetics,  physiopathology,  psychology*
Male
Norepinephrine / blood
Stress, Psychological / physiopathology
Chemical
Reg. No./Substance:
51-41-2/Norepinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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