Document Detail

Supplemental nitrogen inhalation therapy in very low-birth-weight infants with patent ductus arteriosus.
MedLine Citation:
PMID:  16132276     Owner:  NLM     Status:  MEDLINE    
Very low-birth weight infants with patent ductus arteriosus (PDA) accompanied by severe heart failure do not respond to indomethacine therapy. It is essential to stabilize the general condition of these infants until surgical intervention. We tried to regulate the pulmonary blood flow to control congestive heart failure by administering supplemental nitrogen inhalation therapy to six very low-birth-weight infants with PDA. After the inhalation of supplemental nitrogen gas was begun, the arterial oxygen saturation and partial oxygen pressure immediately decreased. Furthermore, the blood pH, systolic pressure, and urine output significantly increased. The infants were well stabilized. Furthermore, there were no complications related to nitrogen gas inhalation. Supplemental nitrogen inhalation therapy is an effective and feasible therapy for severe congestive heart failure in very low-birth-weight infants with PDA.
T Tan; N Mizobe; H Sugiyama; Y Maeda; A Naitou; K Kodera; T Sato; S Nakazawa
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric cardiology     Volume:  26     ISSN:  0172-0643     ISO Abbreviation:  Pediatr Cardiol     Publication Date:    2005 Nov-Dec
Date Detail:
Created Date:  2006-01-19     Completed Date:  2006-08-08     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  8003849     Medline TA:  Pediatr Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  801-4     Citation Subset:  IM    
Division of Neonatology, Perinatal Center, Yamanashi Prefectural Central Hospital, Yamanashi, 409-3898, Japan.
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MeSH Terms
Ductus Arteriosus, Patent / therapy*
Heart Failure / prevention & control
Infant, Newborn
Infant, Very Low Birth Weight*
Nitrogen / therapeutic use*
Respiratory Therapy*
Reg. No./Substance:

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