Document Detail


Supplemental dietary chromium does not influence ACTH, cortisol, or immune responses in young calves inoculated with bovine herpesvirus-1.
MedLine Citation:
PMID:  9027569     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Twelve Holstein bull calves (6 to 8 wk of age) were used to determine the influence of supplemental dietary Cr on ACTH, cortisol, and immune responses of calves experimentally inoculated with bovine herpesvirus-1 (BHV-1). Calves supplemented with Cr received 3 mg Cr/d (Chromium, n = 6) of a high-Cr-yeast product. Following 53 d of treatment, all calves were fitted with jugular catheters, and blood samples were collected every 4 h into tubes containing ETDA. Twenty-four hours later, all calves were inoculated intranasally with BHV-1 (1 x 10(7) plaque-forming units in each naris). Serial blood collection continued at 4-h intervals for 6 d. Plasma was harvested, immediately frozen in liquid nitrogen, and stored at -20 degrees C. Individual rectal temperatures and urine samples were collected at the same time each day. Rectal temperatures were elevated (P < .05) on d 2, 3, 4, and 5 but were not affected by Cr treatment. Treatment with Cr did not affect secretion of ACTH, cortisol, or plasma tumor necrosis factor-alpha, although clear circadian variation in ACTH and cortisol occurred. No differences were detected in the concentrations of trace minerals excreted daily in the urine, lymphocyte proliferative response to mitogen stimulation, and neutrophil bactericidal function. The acute phase proteins, ceruloplasmin and fibrinogen, also were not affected by treatment or viral challenge. These data suggest the Cr supplementation using high-Cr yeast (3 mg/d) did not alter stress responses of calves experimentally inoculated with BHV-1.
Authors:
J D Arthington; L R Corah; J E Minton; T H Elsasser; F Blecha
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of animal science     Volume:  75     ISSN:  0021-8812     ISO Abbreviation:  J. Anim. Sci.     Publication Date:  1997 Jan 
Date Detail:
Created Date:  1997-04-17     Completed Date:  1997-04-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8003002     Medline TA:  J Anim Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  217-23     Citation Subset:  IM    
Affiliation:
Department of Animal Sciences and Industry, Kansas State University, Manhattan 66506, USA.
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MeSH Terms
Descriptor/Qualifier:
Adrenocorticotropic Hormone / blood*
Animals
Antibodies, Viral / metabolism*
Body Temperature / physiology
Body Weight / physiology
Cattle
Cattle Diseases / blood*,  immunology*,  physiopathology
Ceruloplasmin / analysis
Chromium / administration & dosage,  pharmacology*
Circadian Rhythm / physiology
Diet / veterinary*
Dose-Response Relationship, Drug
Fibrinogen / analysis
Food, Fortified
Hematocrit
Hemoglobins / analysis
Herpesviridae Infections / blood,  immunology,  veterinary*
Herpesvirus 1, Bovine / immunology*
Hydrocortisone / blood*
Lymphocytes / pathology
Male
Neutrophils / pathology
Time Factors
Tumor Necrosis Factor-alpha / analysis
Zinc / urine
Chemical
Reg. No./Substance:
0/Antibodies, Viral; 0/Hemoglobins; 0/Tumor Necrosis Factor-alpha; 50-23-7/Hydrocortisone; 7440-47-3/Chromium; 7440-66-6/Zinc; 9001-32-5/Fibrinogen; 9002-60-2/Adrenocorticotropic Hormone; EC 1.16.3.1/Ceruloplasmin

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