Document Detail

Supine hypertension, blood pressure variability and circadian rhythm in autonomic failure: the role of ambulatory intra-arterial monitoring.
MedLine Citation:
PMID:  6518664     Owner:  NLM     Status:  MEDLINE    
Blood pressure variation over 24 h was studied in twelve subjects with suspected or established autonomic failure using ambulatory intra-arterial monitoring. Three subjects who had been previously diagnosed as having orthostatic hypotension due to autonomic failure were found to have normal circulatory reflexes. A generally consistent circadian variation of blood pressure was seen in the other nine subjects, pressure rising gradually from its lowest point early in the morning to a peak during the early part of the night; this pattern was also found during bed rest in four subjects. Supine hypertension (an hourly mean blood pressure of greater than 170/90 mmHg) not suspected from sphygmomanometric readings was observed in four subjects, generally during the night. Heart rate variability was reduced in six subjects while short-term blood pressure variability was markedly increased.
S Mann; G R Bellamy; S N Hunyor; E B Raftery; T Ingall; R Bannister
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical and experimental pharmacology & physiology     Volume:  11     ISSN:  0305-1870     ISO Abbreviation:  Clin. Exp. Pharmacol. Physiol.     Publication Date:    1984 Jul-Aug
Date Detail:
Created Date:  1985-03-07     Completed Date:  1985-03-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0425076     Medline TA:  Clin Exp Pharmacol Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  347-50     Citation Subset:  IM    
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MeSH Terms
Autonomic Nervous System Diseases / physiopathology*
Blood Pressure*
Circadian Rhythm*
Heart Rate
Hypertension / etiology
Monitoring, Physiologic*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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