Document Detail

Supine behaviour predicts the time to death in male Mediterranean fruitflies (Ceratitis capitata).
MedLine Citation:
PMID:  12204122     Owner:  NLM     Status:  MEDLINE    
Over 97% of the 203 male medflies monitored in a lifetime study of their behaviour exhibited what we term supine behaviour (temporary upside-down orientation) starting an average of 16.1 days prior to their death (mean lifespan of 61.7 days). Supine onset increased the mortality risk by 39.5-fold and a unit increase in supine level increased mortality by 26.3%. The discovery that behavioural traits in insects can be used as biomarkers of their health and to predict their time to death has important implications regarding research on morbidity dynamics, behavioural neuroethology and gerontology, and the interpretation of longevity extension in model organisms.
Nikos T Papadopoulos; James R Carey; Byron I Katsoyannos; Nikos A Kouloussis; Hans-Georg Müller; Xueli Liu
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Proceedings. Biological sciences / The Royal Society     Volume:  269     ISSN:  0962-8452     ISO Abbreviation:  Proc. Biol. Sci.     Publication Date:  2002 Aug 
Date Detail:
Created Date:  2002-09-02     Completed Date:  2003-02-21     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  101245157     Medline TA:  Proc Biol Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  1633-7     Citation Subset:  IM    
Laboratory of Applied Zoology and Parasitology, Department of Agriculture, Aristotle University of Thessaloniki, Greece.
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MeSH Terms
Ceratitis capitata / physiology*
Life Expectancy
Proportional Hazards Models
Supine Position*
Time Factors

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