| Superselective intracerebral chemotherapy of malignant tumours with BCNU. Neuroradiological considerations. | |
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MedLine Citation:
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PMID: 3703233 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Early experience shows that: Superselective intra-arterial catheterization above the ophthalmic artery minimizes the orbital complications. Catheterization in a distal branch may lead to the non-infusion of a part of the tumor territory. A much higher concentration of the drug is achieved by superselective intra-arterial infusion than by intravenous injection. Longer infusions seem more efficacious than bolus injection. Early trapping of the drug appears to be essential for therapeutic efficacy. |
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Authors:
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J Théron; J G Villemure; C Worthington; J L Tyler |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Neuroradiology Volume: 28 ISSN: 0028-3940 ISO Abbreviation: Neuroradiology Publication Date: 1986 |
Date Detail:
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Created Date: 1986-06-03 Completed Date: 1986-06-03 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 1302751 Medline TA: Neuroradiology Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 118-25 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Blood-Brain Barrier Brain / pathology Brain Neoplasms / drug therapy*, radiography Carmustine / administration & dosage*, adverse effects, therapeutic use Carotid Artery, Internal Catheterization / adverse effects, methods Cerebral Angiography Glioma / drug therapy*, radiography Humans Injections, Intra-Arterial Necrosis Tomography, X-Ray Computed Vision Disorders / chemically induced |
| Chemical | |
Reg. No./Substance:
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154-93-8/Carmustine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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