Document Detail


Superprecipitation of hybrid actomyosin containing pathologic actin from failing hearts of adults and infants.
MedLine Citation:
PMID:  4029605     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Superprecipitation (SP) of artificial actomyosin, obtained by hybridization of Straub actin from the human myocardium with myosin of normal animal hearts was studied. Actin was prepared from the myocardium of persons who died of congestive heart failure and various non-cardiac diseases, as well as of infants whose death resulted from toxic pneumonia complicated or not with heart failure. It was shown that, in the control hybrid actomyosin, the substitution of normal Straub actin by that from the failing heart resulted in decrease of both the rate and extent of SP. The conclusion was made that both changes in myosin properties and Straub actin underlie the reduced contractility of the myofibrillar protein system in acute and congestive heart failure.
Authors:
N V Karsanov; G I Nizharadze; M P Pirtskhalaishvili; J J Eristavi; O Sh Khundadze; L E Kuchava; I V Pavlenishvili; L V Shengelia
Related Documents :
6246425 - Sustained effectiveness of converting-enzyme inhibition in patients with severe congest...
6710045 - The effects of prazosin in severe congestive heart failure. an echocardiographic study.
2818455 - The use of levodopa, an oral dopamine precursor, in congestive heart failure.
24223815 - Left radial access is preferable to right radial access for the diagnostic or intervent...
19375675 - Clinical presentation and outcome of patients hospitalized for symptomatic in-stent res...
8203335 - Comparison of enalapril versus captopril on left ventricular function and survival thre...
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  General physiology and biophysics     Volume:  4     ISSN:  0231-5882     ISO Abbreviation:  Gen. Physiol. Biophys.     Publication Date:  1985 Aug 
Date Detail:
Created Date:  1985-10-10     Completed Date:  1985-10-10     Revised Date:  2008-11-24    
Medline Journal Info:
Nlm Unique ID:  8400604     Medline TA:  Gen Physiol Biophys     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  417-23     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Actins / isolation & purification*,  metabolism
Actomyosin / isolation & purification*,  metabolism
Adult
Aging
Heart Failure / metabolism*
Humans
Infant
Kinetics
Myocardium / metabolism*
Reference Values
Chemical
Reg. No./Substance:
0/Actins; 9013-26-7/Actomyosin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Voltammetry of tobacco mosaic virus and its isolated protein at the graphite electrode.
Next Document:  Localized conversion in Streptococcus pneumoniae recombination: heteroduplex preference.