Document Detail

Supermicrosurgery and hyaluronic acid: Experimental feasability study of a new method.
MedLine Citation:
PMID:  25447214     Owner:  NLM     Status:  Publisher    
INTRODUCTION: As a technique of anastomosis for vessels of less than 0.8mm in diameter, supermicrosurgery has aroused renewed interest on account of its potential clinical applications. The technical difficulty of surgery at such a small scale necessitates exploration of new methods likely to render the anastomoses accessible and reliable. The aim of this article is to present the results of an experimental study on the feasibility of anastomoses (arterial diameter≤0.5mm), assisted by the injection of hyaluronic acid (HA).
MATERIALS AND METHODS: Ten end-to-end arterial anastomoses of the inferior epigastric artery (diameter≤0.5mm) were performed in 5 rats. An injection of HA had previously been carried out in the vessel lumen and the sutures were made with 12-0 nylon. Immediate and 3-day permeability were controlled and anastomosis times were measured.
RESULTS: Average diameter of the arteries was 0.42mm (range 0.29-0.48mm). Mean anastomosis duration was 19.5min (range 15-23min). The average number of stitches was 6. Immediate patency was 100% with a success rate of 80% at 3 days.
CONCLUSIONS: The properties of HA seem to effectively facilitate anastomoses of arteries with a diameter≤0.5mm. HA provides comfort and promotes safety in performance of exceedingly small-scale surgery. While the results appear promising, but further studies are needed in order to determine the potential toxicity of this method on tissues.
Q Qassemyar; M Gianfermi
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-10-16
Journal Detail:
Title:  Annales de chirurgie plastique et esthetique     Volume:  -     ISSN:  1768-319X     ISO Abbreviation:  Ann Chir Plast Esthet     Publication Date:  2014 Oct 
Date Detail:
Created Date:  2014-12-2     Completed Date:  -     Revised Date:  2014-12-3    
Medline Journal Info:
Nlm Unique ID:  8305839     Medline TA:  Ann Chir Plast Esthet     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier Masson SAS. All rights reserved.
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