Document Detail


Superiority of Measuring Apolipoprotein B to Conventional Lipid Profile predicting risk of Acute Coronary Syndrome in Young People.
MedLine Citation:
PMID:  22081173     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The purpose of this study is to compare the importance and its superiority of apolipoprotein B (apoB) over conventional lipid profile for predicting risk of acute coronary syndrome in young people of Bangladesh. This case-control study was carried out in Department of Cardiology, of Mymensingh Medical College Hospital within the period from June 2009 to May 2010. A total 50 case of 18-45 years of age with first attack of acute coronary syndrome admitted in coronary care unit and 50 healthy controls of same age and sex distribution were studied. Twenty five (50.0%) of the studied case had hyper apoB condition, those low density lipoprotein cholesterol (LDL-C) level was normal, thus conventional lipid profile underestimated the risk. Among the controls 23(46.0%) with high LDL-C had hyper apoB condition. Hyper-ApoB in these controls may cause acute coronary syndrome in future. The present study shows significant association of apolipoprotein B as an independent determinant and estimation of apoB other than conventional lipid profile may be an alternative tool for predicting risk of development of acute coronary syndrome in young people.
Authors:
G P Aditya; M A Bari; M S Bari
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Mymensingh medical journal : MMJ     Volume:  20     ISSN:  1022-4742     ISO Abbreviation:  Mymensingh Med J     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-11-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9601799     Medline TA:  Mymensingh Med J     Country:  Bangladesh    
Other Details:
Languages:  eng     Pagination:  578-85     Citation Subset:  IM    
Affiliation:
Dr Gana Pati Aditya, Emergency Medical Officer, Mymensingh Medical College Hospital, Mymensingh, Bangladesh; E-mail: ganapati. aditya@yahoo.com.
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