Document Detail


Superior vena cava thrombosis and obstructive sleep apnea in a patient with familial Mediterranean fever.
MedLine Citation:
PMID:  9671044     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Familial Mediterranean fever (FMF), a paroxysmal, self-limited, inflammatory disease of unknown etiology, may result in thrombotic complications after the development of nephrotic syndrome due to amyloidosis. It has been suggested that there is increased thrombogenic activity in the blood of patients with FMF who did not develop nephrotic syndrome. We describe a patient with FMF who presented with thrombosis in the superior vena cava (SVC) in the absence of nephrotic syndrome, and discuss the contributory role of increased procoagulant activity detected in this disorder. Moreover, the patient was proved to have obstructive sleep apnea (OSA) which we believe was secondary to SVC thrombosis that lead to soft tissue edema in the upper airways. To our knowledge, this is the second reported case in the literature in which OSA occurred secondary to the SVC thrombosis.
Authors:
Y Ustündag; Y Bayraktar; S Emri
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of the medical sciences     Volume:  316     ISSN:  0002-9629     ISO Abbreviation:  Am. J. Med. Sci.     Publication Date:  1998 Jul 
Date Detail:
Created Date:  1998-08-13     Completed Date:  1998-08-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370506     Medline TA:  Am J Med Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  53-5     Citation Subset:  AIM; IM    
Affiliation:
Department of Internal Medicine, Hacettepe University School of Medicine, Ankara, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Angiography
Blood Coagulation Disorders / physiopathology
Familial Mediterranean Fever / complications*,  genetics
Humans
Male
Middle Aged
Polysomnography
Sleep Apnea Syndromes / physiopathology*
Superior Vena Cava Syndrome / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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