| Superior thyroid artery mean peak systolic velocity for the diagnosis of thyrotoxicosis in Japanese patients. | |
| | |
MedLine Citation:
|
PMID: 20513982 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Thyrotoxicosis with diffuse thyroid disease can be caused by Graves' disease (GD) or destructive thyroiditis (DT). Optimal treatment of the underlying condition requires a prompt and accurate method for the diagnosis of thyrotoxicosis. This study evaluated measurement of the mean peak systolic velocity of the superior thyroid artery (STA-PSV) by ultrasonography in detecting thyrotoxicosis in Japanese patients. We recruited 44 patients with untreated GD, 13 with DT, 55 with treated GD, and 49 subjects without thyroid disease. Blood samples were taken to analyze thyroid function and STA-PSV was measured by ultrasonography. The mean STA-PSV was the highest in the untreated GD group, followed by treated GD patients and then those with DT. Receiver operating characteristic curves of the STA-PSV values demonstrated that the area under the curve required discriminating untreated GD from DT was 0.941. The optimal sensitivity and specificity were 83.7% and 92.3%, respectively, using 45 cm/sec as the cutoff value. In conclusion measurement of STA-PSV by ultrasonography is useful for the diagnosis of thyrotoxicosis in Japanese patients. |
| | |
Authors:
|
Toyoyoshi Uchida; Kageumi Takeno; Masahiro Goto; Rei Kanno; Sayaka Kubo; Satomi Takahashi; Kousuke Azuma; Ken Sakai; Yoshio Fujitani; Takahisa Hirose; Ryuzo Kawamori; Hirotaka Watada |
Publication Detail:
|
Type: Controlled Clinical Trial; Journal Article |
Journal Detail:
|
Title: Endocrine journal Volume: 57 ISSN: 1348-4540 ISO Abbreviation: Endocr. J. Publication Date: 2010 |
Date Detail:
|
Created Date: 2010-06-01 Completed Date: 2010-09-07 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9313485 Medline TA: Endocr J Country: Japan |
Other Details:
|
Languages: eng Pagination: 439-43 Citation Subset: IM |
Affiliation:
|
Department of Medicine, Juntendo University, Graduate School, Bunkyo-ku, Tokyo, Japan. uchitoyo@juntendo.ac.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Arteries Asian Continental Ancestry Group* Blood Flow Velocity / physiology Female Graves Disease / blood, physiopathology Humans Male Middle Aged Regional Blood Flow / physiology* Sensitivity and Specificity Systole Thyroid Gland / blood supply*, pathology Thyroid Hormones / analysis, blood Thyrotoxicosis / blood, diagnosis*, physiopathology Ultrasonography, Doppler, Color |
| Chemical | |
Reg. No./Substance:
|
0/Thyroid Hormones |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Introduction of a three-dimensional and layered (TDL) culture, a novel primary co-culture method for...
Next Document: Erratum:Pituitary and Stalk Lesions (Infundibulo-hypophysitis) Associated with Immunoglobulin G4-rel...