Document Detail

Superior limbic keratoconjunctivitis associated with cosmetic soft contact lens wear.
MedLine Citation:
PMID:  6882249     Owner:  NLM     Status:  MEDLINE    
Thirteen patients who wore soft contact lenses were seen with a syndrome consistent with superior limbic keratoconjunctivitis. An irregular epithelial surface, punctate staining with fluorescein, and subepithelial infiltrates were found on the superior aspect of the corneas in association with hyperemia of the superior bulbar conjunctivae. The keratoconjunctivitis persisted as long as 15 months after discontinuation of lens wear. Patch testing with ophthalmic vehicle preservatives, performed on seven patients, failed to show a consistent hypersensitivity to any of the tested compounds, and three patients had used only preservative-free saline for lens care. The etiology of this syndrome is unknown.
D J Fuerst; J Sugar; S Worobec
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Archives of ophthalmology     Volume:  101     ISSN:  0003-9950     ISO Abbreviation:  Arch. Ophthalmol.     Publication Date:  1983 Aug 
Date Detail:
Created Date:  1983-09-09     Completed Date:  1983-09-09     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7706534     Medline TA:  Arch Ophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1214-6     Citation Subset:  AIM; IM    
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MeSH Terms
Contact Lenses, Hydrophilic / adverse effects*
Dexamethasone / therapeutic use
Hypersensitivity / diagnosis
Keratoconjunctivitis / drug therapy,  etiology*
Ophthalmic Solutions / adverse effects
Patch Tests
Grant Support
Reg. No./Substance:
0/Ophthalmic Solutions; 50-02-2/Dexamethasone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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