Document Detail


Superficial siderosis of the central nervous system: a rare cause of dementia with therapeutic consequences.
MedLine Citation:
PMID:  22291165     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A 75-year-old patient was evaluated for dementia. His past medical history included an ischaemic cardiomyopathy treated with aspirin daily. His neurological examination showed mild ataxia syndrome and central deafness. The neuropsychological examination did not suggest Alzheimer's disease. No specific aetiology was found from biological investigations, but MRI scans revealed a superficial siderosis, which was further confirmed with CSF exams. This case highlights the interest of MRI with echo-gradient-T2 weighted sequences in patients investigated for memory disorders. Once the diagnosis is known, specific preventive measures have to be taken: searching for a treatable source of bleeding and the interruption of antiplatelet aggregation or anticoagulant treatments.
Authors:
Anne-Laure Dubessy; Renata Ursu; Didier Maillet; Alexandre Augier; Johan Le Guilloux; Antoine F Carpentier; Catherine Belin
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-29
Journal Detail:
Title:  Age and ageing     Volume:  -     ISSN:  1468-2834     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375655     Medline TA:  Age Ageing     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Neurology, CHU Avicenne AP-HP-Paris, 125 route de Stalingrad, Bobigny, France.
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