Document Detail


Superficial siderosis: a case report and review of the literature.
MedLine Citation:
PMID:  17205075     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: A 48-year-old man with a past history of a car-accident-induced coma at the age of 3 years and spontaneous bilateral subdural hematomas at the age of 34 years presented with a 2-year history of worsening gait difficulties, clumsiness and dysarthria. CT scans of the brain taken during the 6 months leading up to his presentation had revealed chronic subarachnoid hemorrhage, but angiograms had not been able to identify the source of bleeding. INVESTIGATIONS: Neurological examination, brain MRI scan, lumbar puncture, four-vessel cerebral angiogram and spinal angiogram. DIAGNOSIS: Superficial siderosis; a complete review of the current literature on the condition is provided. MANAGEMENT: Iron chelating agents.
Authors:
Michael Levy; Christine Turtzo; Rafael H Llinas
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Nature clinical practice. Neurology     Volume:  3     ISSN:  1745-834X     ISO Abbreviation:  -     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2007-01-05     Completed Date:  2007-02-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101261799     Medline TA:  Nat Clin Pract Neurol     Country:  England    
Other Details:
Languages:  eng     Pagination:  54-8; quiz 59     Citation Subset:  IM    
Affiliation:
Johns Hopkins Hospital, Baltimore, MD, USA. mlevy@jhmi.edu
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MeSH Terms
Descriptor/Qualifier:
Chronic Disease
Humans
Iron Chelating Agents / therapeutic use
Magnetic Resonance Imaging*
Male
Middle Aged
Siderosis / complications*,  drug therapy,  pathology*
Subarachnoid Hemorrhage / etiology*,  pathology*
Chemical
Reg. No./Substance:
0/Iron Chelating Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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