Document Detail


Superficial thrombophlebitis: A new clinical manifestation of the immune reconstitution inflammatory syndrome in a patient with HIV infection.
MedLine Citation:
PMID:  20881830     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Skin manifestations of immune reconstitution inflammatory syndrome in response to highly active antiretroviral therapy may account for up to 50% of the clinical presentations in this syndrome. Viable or dying infective antigens, host antigens, tumoral antigens, and others may target immune reconstitution inflammatory syndrome, resulting in a wide spectrum of clinical manifestations. We describe a 26-year-old HIV-infected man who had started highly active antiretroviral therapy a few months earlier. He developed multiple linear nodules following the superficial veins in both legs. Histopathologic examination demonstrated a mostly septal panniculitis with features of superficial thrombophlebitis. We propose that superficial thrombophlebitis should be added to the list of clinical manifestations of this newly observed immune restoration disease.
Authors:
Inmaculada Alcaraz; Juan Maria Revelles; Diana Camacho; Rosario Haro; María Jesús Fernández-Aceñero; Manuel Fernández-Guerrero; Luis Requena
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American Journal of dermatopathology     Volume:  32     ISSN:  1533-0311     ISO Abbreviation:  Am J Dermatopathol     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7911005     Medline TA:  Am J Dermatopathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  846-9     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Universidad Autónoma, Madrid, Spain. ialcarazl@fjd.es
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