Document Detail

Sunscreening agent intolerance: contact and photocontact sensitization and contact urticaria.
MedLine Citation:
PMID:  2196288     Owner:  NLM     Status:  MEDLINE    
Reports in the literature of sensitization associated with many commonly used sunscreening agents including p-aminobenzoic acid (PABA), PABA derivatives, anthranilates, salicylates, cinnamates, benzophenones, and dibenzoylmethane derivatives are reviewed. Several of these case reports involved subjects with various photodermatoses, implicating enhanced sensitivity of the patient's skin to both light and chemicals. Despite the widespread use of sunscreens, the small number of published reports of contact and photocontact sensitization to these agents suggests that either such sensitization is less than commonly perceived or is underreported. Establishment of a registry for reporting adverse effects associated with sunscreening agents would help to characterize the incidence of sensitization.
S H Dromgoole; H I Maibach
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of the American Academy of Dermatology     Volume:  22     ISSN:  0190-9622     ISO Abbreviation:  J. Am. Acad. Dermatol.     Publication Date:  1990 Jun 
Date Detail:
Created Date:  1990-08-23     Completed Date:  1990-08-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7907132     Medline TA:  J Am Acad Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1068-78     Citation Subset:  IM    
Clinical Research and Development Department, Herbert Laboratories, Irvine, CA.
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MeSH Terms
4-Aminobenzoic Acid / adverse effects,  analogs & derivatives
Dermatitis, Contact / etiology*
Excipients / adverse effects
Photosensitivity Disorders / chemically induced*
Sunscreening Agents / administration & dosage,  adverse effects*
United States
Urticaria / chemically induced*
Reg. No./Substance:
0/Excipients; 0/Sunscreening Agents; 150-13-0/4-Aminobenzoic Acid; 21245-02-3/padimate-O

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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