Document Detail


Summary of ASHP/IDSA/SIDP vancomycin monitoring recommendations: a focus on osteomyelitis.
MedLine Citation:
PMID:  19634847     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Vancomycin has been used extensively for the treatment of Gram-positive bacterial infections, especially in cases of methicillin-resistant Staphylococcus aureus (MRSA). Despite long-term use, many uncertainties have remained regarding appropriate dosing, monitoring, and toxicity risks. In January 2009, a committee representing the American Society of Health-System Pharmacists (ASHP), the Infectious Diseases Society of America (IDSA), and the Society of Infectious Diseases Pharmacists (SIDP) released recommendations for vancomycin monitoring. As osteomyelitis patients are frequent recipients of vancomycin, this article provides a summary of the recommendations in reference to loading and maintenance doses, trough concentration monitoring, frequency of monitoring, and risk of toxicities.
Authors:
Katherine M Malloy; George A Davis
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Orthopedics     Volume:  32     ISSN:  1938-2367     ISO Abbreviation:  Orthopedics     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-07-28     Completed Date:  2009-10-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7806107     Medline TA:  Orthopedics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  499     Citation Subset:  IM    
Affiliation:
University of Kentucky Hospital, Department of Pharmacy, 800 Rose Street, Lexington, KY 40536-2093, USA.
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MeSH Terms
Descriptor/Qualifier:
Humans
Osteomyelitis / drug therapy*
Practice Guidelines as Topic*
Prescriptions / standards*
United States
Vancomycin / therapeutic use*
Chemical
Reg. No./Substance:
1404-90-6/Vancomycin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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