Document Detail

Sumatriptan in patients with postdural puncture headache.
MedLine Citation:
PMID:  10759937     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine the efficacy of sumatriptan in the management of patients presenting for an epidural blood patch for the management of postdural puncture headache. BACKGROUND: Postdural puncture headache can be quite severe, requiring invasive therapy (ie, epidural blood patch). Sumatriptan has been used successfully in patients with postdural puncture headache, however, its use has not been investigated in a controlled fashion. METHODS: Ten patients with postdural puncture headache presenting for an epidural blood patch were given either saline or sumatriptan subcutaneously. The severity of the headache was evaluated at baseline and 1 hour following injection. If the headache remained severe, an epidural blood patch was performed. RESULTS: Only one patient in each group received relief from the injection. CONCLUSIONS: We do not recommend sumatriptan in patients who have exhausted conservative management of postdural puncture headache.
N R Connelly; R K Parker; A Rahimi; C S Gibson
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Headache     Volume:  40     ISSN:  0017-8748     ISO Abbreviation:  Headache     Publication Date:  2000 Apr 
Date Detail:
Created Date:  2000-09-27     Completed Date:  2000-09-27     Revised Date:  2009-02-02    
Medline Journal Info:
Nlm Unique ID:  2985091R     Medline TA:  Headache     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  316-9     Citation Subset:  IM    
Department of Anesthesiology, Baystate Medical Center, Springfield, MA 01199, USA.
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MeSH Terms
Anesthesia, Epidural / adverse effects
Blood Patch, Epidural*
Headache / drug therapy*,  etiology,  therapy*
Injections, Subcutaneous
Serotonin Agonists / therapeutic use*
Spinal Puncture / adverse effects
Sumatriptan / therapeutic use*
Reg. No./Substance:
0/Serotonin Agonists; 103628-46-2/Sumatriptan

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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