| Sumatriptan in patients with postdural puncture headache. | |
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MedLine Citation:
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PMID: 10759937 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine the efficacy of sumatriptan in the management of patients presenting for an epidural blood patch for the management of postdural puncture headache. BACKGROUND: Postdural puncture headache can be quite severe, requiring invasive therapy (ie, epidural blood patch). Sumatriptan has been used successfully in patients with postdural puncture headache, however, its use has not been investigated in a controlled fashion. METHODS: Ten patients with postdural puncture headache presenting for an epidural blood patch were given either saline or sumatriptan subcutaneously. The severity of the headache was evaluated at baseline and 1 hour following injection. If the headache remained severe, an epidural blood patch was performed. RESULTS: Only one patient in each group received relief from the injection. CONCLUSIONS: We do not recommend sumatriptan in patients who have exhausted conservative management of postdural puncture headache. |
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Authors:
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N R Connelly; R K Parker; A Rahimi; C S Gibson |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Headache Volume: 40 ISSN: 0017-8748 ISO Abbreviation: Headache Publication Date: 2000 Apr |
Date Detail:
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Created Date: 2000-09-27 Completed Date: 2000-09-27 Revised Date: 2009-02-02 |
Medline Journal Info:
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Nlm Unique ID: 2985091R Medline TA: Headache Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 316-9 Citation Subset: IM |
Affiliation:
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Department of Anesthesiology, Baystate Medical Center, Springfield, MA 01199, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anesthesia, Epidural / adverse effects Blood Patch, Epidural* Female Headache / drug therapy*, etiology, therapy* Humans Injections, Subcutaneous Male Serotonin Agonists / therapeutic use* Spinal Puncture / adverse effects Sumatriptan / therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Serotonin Agonists; 103628-46-2/Sumatriptan |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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