Document Detail

Sulphur-induced polioencephalomalacia in lambs.
MedLine Citation:
PMID:  8730674     Owner:  NLM     Status:  MEDLINE    
An outbreak of polioencephalomalacia affected 16 of 46 Swaledale lambs and five of 25 Scottish blackface lambs 15 to 32 days after they were introduced to an ad libitum concentrate ration containing 0.43 per cent sulphur. The clinical signs were acute and included depression central blindness and head-pressing, but no hyperaesthesia, nystagmus, dorsiflexion of the neck or opisthotonos were observed. Treatment of the affected lambs with vitamin B1, dexamethasone and antibiotics was associated with a prolonged recovery period, though no further cases were identified after vitamin B1 had been given parenterally to all the lambs at risk.
J C Low; P R Scott; F Howie; M Lewis; J FitzSimons; J A Spence
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Veterinary record     Volume:  138     ISSN:  0042-4900     ISO Abbreviation:  Vet. Rec.     Publication Date:  1996 Apr 
Date Detail:
Created Date:  1996-09-25     Completed Date:  1996-09-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0031164     Medline TA:  Vet Rec     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  327-9     Citation Subset:  IM    
Scottish Agricultural College Veterinary Services (Edinburgh), Bush Estate, Penicuik, Midlothian.
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MeSH Terms
Animal Feed / adverse effects,  analysis
Dexamethasone / therapeutic use
Disease Outbreaks / veterinary*
Encephalomalacia / drug therapy,  physiopathology,  veterinary*
Sheep Diseases / chemically induced*,  drug therapy,  physiopathology
Sulfur / adverse effects*
Thiamine / therapeutic use
Reg. No./Substance:
50-02-2/Dexamethasone; 59-43-8/Thiamine; 7704-34-9/Sulfur

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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