| Sulfation of tea polysaccharides: synthesis, characterization and hypoglycemic activity. | |
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MedLine Citation:
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PMID: 20026346 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Neutral polysaccharides (NTPS) and acid polysaccharides (ATPS) from tea leaves were obtained on a D315 macroporous anion-exchange resin column chromatography. NTPS and ATPS were sulfated by the pyridine-sulfonic acid method to obtain NTPS-S and ATPS-S. It was found that NTPS was easier sulfated than ATPS. There are strong characteristic absorption peaks located in 1258 cm(-1), 1146 cm(-1), 832 cm(-1) and 617 cm(-1) in the FTIR spectra of sulfated polysaccharides. Sulfation of polysaccharides also affected the endothermic and exothermic peaks via the DSC scan analysis. The appearance of exothermic peaks in both NTPS-S and ATPS-S indicated that the redox reaction might happen. The comparative study of hypoglycemic effect on mice showed that the sulfation of polysaccharides significantly improved hypoglycemic activity. |
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Authors:
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Yuanfeng Wang; Yonghua Peng; Xinlin Wei; Zhiwei Yang; Jianbo Xiao; Zhengyu Jin |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-12-22 |
Journal Detail:
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Title: International journal of biological macromolecules Volume: 46 ISSN: 1879-0003 ISO Abbreviation: Int. J. Biol. Macromol. Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-02-15 Completed Date: 2010-05-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7909578 Medline TA: Int J Biol Macromol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 270-4 Citation Subset: IM |
Copyright Information:
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2009 Elsevier B.V. All rights reserved. |
Affiliation:
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College of Life and Environment Science, Shanghai Normal University, Shanghai, China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Glucose / drug effects Calorimetry, Differential Scanning Carbohydrate Conformation Hypoglycemia / drug therapy* Male Mice Microscopy, Atomic Force Polysaccharides / chemical synthesis*, chemistry, therapeutic use* Spectrophotometry, Infrared Sulfates / metabolism* Tea / chemistry* |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 0/Polysaccharides; 0/Sulfates; 0/Tea |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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