Document Detail

Sulfated polysaccharides and cell differentiation in the sea urchin embryo.
MedLine Citation:
PMID:  6238860     Owner:  NLM     Status:  MEDLINE    
The synthesis of sulfated polysaccharides during the embryonic development of Paracentrotus lividus has been investigated by incorporation of radioactive sulfate, glucose, glucosamine and fucose. The following substances become labelled: fucan sulfate (approximately 60%), heparan sulfate (approximately 20%) and dermatan sulfate (approximately 20%), and possibly a very slight amount of chondroitin sulfate. In animalized and vegetalized embryos, the rate of incorporation is significantly reduced, and furthermore dermatan sulfate is almost absent in animalized embryos. It is concluded that this substance is associated with the differentiation of vegetative cells, possibly the mesenchyme cells.
H Løvtrup-Rein; S Løvtrup
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Experimental cell biology     Volume:  52     ISSN:  0304-3568     ISO Abbreviation:  Exp. Cell Biol.     Publication Date:  1984  
Date Detail:
Created Date:  1985-01-24     Completed Date:  1985-01-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7701827     Medline TA:  Exp Cell Biol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  383-8     Citation Subset:  IM    
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MeSH Terms
Cell Differentiation
Embryo, Nonmammalian / cytology
Fucose / metabolism
Glucosamine / metabolism
Glucose / metabolism
Glycosaminoglycans / biosynthesis*
Sea Urchins / embryology*
Sulfates / metabolism
Sulfur Radioisotopes / diagnostic use
Tritium / diagnostic use
Reg. No./Substance:
0/Glycosaminoglycans; 0/Sulfates; 0/Sulfur Radioisotopes; 10028-17-8/Tritium; 3416-24-8/Glucosamine; 3713-31-3/Fucose; 50-99-7/Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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