| Sulfated modification of the polysaccharide from Cordyceps_gunnii mycelia and its biological activities. | |
| | |
MedLine Citation:
|
PMID: 23218378 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
A chemically new sulfated polysaccharide (SPS50) was prepared from the water soluble polysaccharide (PS50), isolated from Cordyceps_gunnii mycelia, by concentrated sulfuric acid method. The yield of crude SPS50 was 62.34% and its specific rotation was [α](D)(20)=-36.75°. The structural characteristics of this chemically sulfated polysaccharide were determined based on the infrared analysis (IR), high performance liquid chromatography (HPLC) and sodium dodecyl sulfate polyacrylamide gel electropheresis (SDS-PAGE). Its biological properties including anti-oxidant and anti-tumor activities were also investigated. The results showed that the anti-oxidant capacity of SPS50 was not as good as SP50 and the anti-tumor activity of SPS50 was much better than PS50. SPS50 showed evident growth inhibition on K562 cells. The tumor inhibition ratio of SPS50 against K562 cells was 69.92%. |
| | |
Authors:
|
Zhen-Yuan Zhu; Yang Liu; Chuan-Ling Si; Jing Yuan; Qiang Lv; Yuan-Yuan Li; Guo-Ling Dong; An-Jun Liu; Yong-Min Zhang |
Related Documents
:
|
15867248 - Antimetastatic effect of salvicine on human breast cancer mda-mb-435 orthotopic xenogra... 2777418 - Detection by in situ hybridization of messenger rnas of collagen types i and iv in muri... 10491398 - Function of alpha3beta1-tetraspanin protein complexes in tumor cell invasion. evidence ... 1319408 - Malignant transformation of nih-3t3 cells after subcutaneous co-injection with a recons... 16183528 - Endocrine tumours of the gastrointestinal tract. surgical treatment of neuroendocrine m... 21222278 - Ubiquitin family members in the regulation of the tumor suppressor p53. |
Publication Detail:
|
Type: Journal Article Date: 2012-10-12 |
Journal Detail:
|
Title: Carbohydrate polymers Volume: 92 ISSN: 1879-1344 ISO Abbreviation: Carbohydr Polym Publication Date: 2013 Jan |
Date Detail:
|
Created Date: 2012-12-10 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8307156 Medline TA: Carbohydr Polym Country: England |
Other Details:
|
Languages: eng Pagination: 872-6 Citation Subset: IM |
Copyright Information:
|
Copyright © 2012 Elsevier Ltd. All rights reserved. |
Affiliation:
|
Key Laboratory of Food Nutrition and Safety, Ministry of Education, College of Food Science and Biotechnology, Tianjin University of Science and Technology, Tianjin 300457, PR China. Electronic address: zhyuanzhu@tust.edu.cn. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Preparation and characterization of bagasse/HDPE composites using multi-walled carbon nanotubes.
Next Document: A novel green gelatin-agar microencapsulation system with P. urinaria as an improved anti-A. niger m...