Document Detail


Sulfadiazine-induced nephrolithiasis detected by spiral CT scan.
MedLine Citation:
PMID:  15025231     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nephrolithiasis is a known complication of the use of sulfadiazine in the treatment of cerebral toxoplasmosis. Radiographic diagnosis of this complication has historically been challenging. Between March 1999 and June 2002, 11 patients were treated for cerebral toxoplasmosis with sulfadiazine-containing therapy. Four of these patients (36.4%) developed nephrolithiasis during this period. Case patients had received sulfadiazine for a median of 35.5 days prior to nephrolithiasis. All cases were diagnosed by spiral CT scans. Although studies are needed to evaluate the sensitivity and specificity of this modality, spiral CT may aid in the diagnosis of sulfadiazine-induced nephrolithiasis.
Authors:
Stephanie A Lee; Christopher W James; Susan Szabo; Robert M Dressler
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Delaware medical journal     Volume:  76     ISSN:  0011-7781     ISO Abbreviation:  Del Med J     Publication Date:  2004 Feb 
Date Detail:
Created Date:  2004-03-17     Completed Date:  2004-04-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370077     Medline TA:  Del Med J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  59-63     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine at Christiana Care Health Services, Wilmington, Delaware, USA.
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MeSH Terms
Descriptor/Qualifier:
AIDS-Related Opportunistic Infections / drug therapy*
Adult
Humans
Male
Sulfadiazine / adverse effects*
Tomography, X-Ray Computed
Toxoplasmosis, Cerebral / drug therapy*
Ureteral Calculi / chemically induced*,  radiography*
Chemical
Reg. No./Substance:
68-35-9/Sulfadiazine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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